H
HBc

Hepatitis B core antigen

HBsAg

Hepatitis B surface antigen

HBV

Hepatitis B virus

Hct

Hematocrit

HCT/Ps

Human cells, tissues, or cellular or tissue-based products

HCV

Hepatitis C virus

Helper-T cell

Sets of T-lymphocytes that specifically are involved in the differentiation of B-lymphocytes into antibody-secreting cells.  Loss of T-helper cells, as in HIV infection, leads to immunosuppression.  There is also T-cell help of T-cell function.  TH1 and TH2 are now recognized, TH1 helping with cellular, TH2 with humoral immunity.  Most helper T cells bear the CD4 surface antigen.

Hematopoietic

Referring to the production of blood.

Hematopoietic Progenitor Cell Therapy

The infusion of HPC products with the intent of providing effector cells in support of therapy of disease or other cell therapy.

Hematopoietic Progenitor Cells (HPC)

Self-renewing and multi-potent stem cells capable of maturation into any of the hematopoietic lineages, lineage-restricted pluri-potent progenitor cells, and committed progenitor cells, regardless of tissue source (bone marrow, umbilical cord blood, peripheral blood, and other tissue sources).

Herpes virus

A group of large DNA viruses: Herpes simplex causes cold-sores and genital herpes; Varicella-zoster causes chicken-pox and shingles; cytomegalovirus causes congenital abnormalities and is an opportunistic pathogen; Epstein-Barr virus (EBV) causes glandular fever.  Herpes simplex type 2 and EBV are associated with human tumors (cervical carcinoma for the former and Burkett’s lymphoma and nasopharyngeal carcinoma in the case of EBV).  Herpes simplex establishes a lifelong latent infection of sensory neurons in human dorsal root ganglia and has a tendency to resurgence if the immune system is suppressed (causing shingles).

Hgb

Hemoglobin

Histocompatability

Pertaining to the similarity of tissues between different individuals.  Literally the ability of tissues to get along.  The major histocompatibility complex (MHC) in humans is termed Human Leukocyte Antigens (HLA).

HIV

Human Immunodeficiency Virus

HLA

Human leukocyte antigen

Homologous Use

The replacement or supplementation of a recipient’s cells or tissues with an cell therapy product that performs the same basic function or functions in the recipient as in the donor.

HPC-A

Hematopoietic Progenitor Cell, Apheresis

HPC-C

Hematopoietic Progenitor Cell, Cord Blood

HPC-M

Hematopoietic Progenitor Cell, Marrow

HSA

Human serum albumin